Interpretation of Hepatitis B Serologic Test Results

  

HBsAg	negative	Susceptible
anti–HBc	negative
anti–HBs	negative
HBsAg	negative	Immune due to natural infection
anti–HBc	positive
anti–HBs	positive
HBsAg	negative	Immune due to Hepatitis B vaccination
anti–HBc	negative
anti–HBs	positive
HBsAg	positive	Acutely infected
anti–HBc	positive
IgM anti–HBc	positive
anti–HBs	negative
HBsAg	positive	Chronically infected
anti–HBc	positive
IgM anti–HBc	negative
anti–HBs	negative
HBsAg	negative	Interpretation unclear; four possibilities: 1. Resolved infection 2. False–positive anti–HBc, thus susceptible 3. “Low level” chronic infection 4. Resolving acute infection
anti–HBc	positive
anti–HBs	negative